There are currently 48 active clinical trials seeking participants for Autism research studies. The states with the highest number of trials for Autism participants are California, Florida, Ohio and New York.
Improving Academic and Social Functioning in Middle-Schoolers With Autism
NCT06705907
Recruiting
The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD). One of the interventions focuses on teaching parents and adolescent skills to help improve their social functioning and the other focuses on teaching parents and adolescents skills to improve organization, planning, and study skills. Eligible participants will be randomly (like a coin flip) assigned to attend one of the two interventions.
Gender:
ALL
Ages:
Between 10 years and 15 years
Trial Updated:
02/03/2025
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Autism, Autism Spectrum Disorder
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Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder
NCT06670040
Recruiting
Evaluate the efficacy of accelerated theta burst stimulation (aTBS) in reducing depressive symptoms in autism spectrum disorder (ASD)
Gender:
ALL
Ages:
Between 13 years and 26 years
Trial Updated:
10/31/2024
Locations: Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio
Conditions: ASD, Autism Spectrum Disorder, Autism, Depression - Major Depressive Disorder, MDD
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Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
NCT03434080
Recruiting
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses laser light shone through the scalp to look at blood flow in the brain which increases with movement. EEG records electrical activity in the brain. Little is known about brain activity while children learn new motor skills. Researchers want to learn more about how small children with and without cerebral palsy use their brain to control their body. This ma... Read More
Gender:
ALL
Ages:
Between 3 months and 5 years
Trial Updated:
03/29/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Autism, Cerebral Palsy
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Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
NCT01778504
Recruiting
Background: - Many psychiatric, behavioral, and developmental disorders are genetic. This means that they tend to run in families. Some begin in childhood, while others do not appear until adulthood. Researchers want to look at people of all ages who have these disorders that started in childhood. They will also look at relatives of people with these disorders. This information will allow doctors to learn more about childhood behavioral problems and how they are inherited. It may also help doct... Read More
Gender:
ALL
Ages:
99 years and below
Trial Updated:
03/28/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Neurological Disorder, Autism, Sleep
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Biomarkers Research in Anxiety for Validation and Efficacy
NCT06221176
Recruiting
A within-subjects design will be used for this preliminary investigation of four biomarkers across two contexts of use: prediction of treatment response (i.e., stratification) and quantification of response (i.e., change).
Gender:
ALL
Ages:
Between 3 years and 6 years
Trial Updated:
03/10/2025
Locations: Boston Children's Hospital, Two Brookline Place, Brookline, Massachusetts
Conditions: Autism, Autism Spectrum Disorder
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A Strength-Based Employment Maintenance Program for Individuals on the Autism Spectrum
NCT06255925
Recruiting
The investigators are looking to evaluate how effective a training program that focuses on character strengths may be in improving job maintenance skills in young adults. The investigators are examining the effects of this intervention in young adults who feel they would like to help in improving their satisfaction with work, and in keeping their jobs.
Gender:
ALL
Ages:
Between 14 years and 26 years
Trial Updated:
03/06/2025
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Autism
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Use of Eye Tracking to Aid in Autism Risk Detection
NCT06471504
Recruiting
The study will use a non-invasive remote eye-tracking system (Eyelink Portable Duo) to acquire a short series of eye-tracking measures.
Gender:
ALL
Ages:
Between 12 months and 48 months
Trial Updated:
03/04/2025
Locations: Riley Hospital for Children, Indianapolis, Indiana
Conditions: Autism
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Trial of Diphenhydramine for Sleep in Children With Autism
NCT05501678
Recruiting
The purpose of this study is to examine the effect of diphenhydramine on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Diphenhydramine is an anti-histaminergic agent with strong hypnotic properties. To accomplish this, the investigators will use a randomized double-blind placebo-controlled crossover 8-week study design to examine the effect of diphenhydramine on sleep physiology as assessed by polysomnography (PSG), actigraphy, circadian rhythm, and clinical measures.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
02/28/2025
Locations: Stanford University, Stanford, California
Conditions: Autism, Autism Spectrum Disorder
Register for Updates
Pilot Trial of Pregnenolone in Autism
NCT02627508
Recruiting
This is a research study to examine the tolerability and effectiveness of pregnenolone in individuals with autism. Pregnenolone is a naturally occurring steroid hormone in the brain that has been implicated in treating various psychiatric conditions. The investigators hope to learn the effects and safety of using pregnenolone in reducing irritability and sensitivity to sensory differences and improving social communication in individuals with autism. The investigators hope by studying the effect... Read More
Gender:
ALL
Ages:
Between 14 years and 25 years
Trial Updated:
02/28/2025
Locations: Stanford University School of Medicine, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
Register for Updates
Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children
NCT06472115
Recruiting
This study will examine the potential effectiveness of a virtually delivered parent-mediated intervention for insistence on sameness behaviors in autism and investigate 1) whether caregivers can learn to deliver the adapted Supportive Parenting for Anxious Childhood emotions (SPACE) intervention for IS via telehealth and 2) whether children will show greater improvement in IS behaviors.
Gender:
ALL
Ages:
Between 6 years and 11 years
Trial Updated:
02/21/2025
Locations: Jennifer Phillips, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
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Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD
NCT04532424
Recruiting
Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.
Gender:
ALL
Ages:
Between 12 years and 45 years
Trial Updated:
02/14/2025
Locations: Stanford University, Stanford, California
Conditions: Autism Spectrum Disorder, Autism, Asperger Syndrome
Register for Updates
Trial of Zolpidem for Sleep in Children with Autism
NCT05540574
Recruiting
The purpose of this study is to examine the effect of zolpidem on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Zolpidem is a nonbenzodiazepine GABAa receptor agonist drug that acts as a hypnotic. To accomplish this, the investigators will use a randomized double-blind placebo-controlled crossover 8-week study design to examine the effect of zolpidem on sleep physiology as assessed by polysomnography (PSG), actigraphy, circadian rhythm, and clinical measures.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
02/10/2025
Locations: Stanford University, Stanford, California
Conditions: Autism, Autism Spectrum Disorder
Register for Updates